What is a TCA Drug Test?
Tricyclic Antidepressants (TCA) is a type of drug that are typically prescribed by mental health practitioners, such as psychiatrists and psychologists, for the treatment of mental health conditions such as depression and anxiety (MedlinePlus, n.d.; University of Rochester, n.d.).
This medication was one of the original antidepressant medications available and can be very effective for treatment. However, prescribed TCAs have led to many overdose-related deaths in the United States, which means it is essential that the dosage is right.
To assist health care providers in prescribing the right dose, the TCA drug test can be administered to assess the amount of TCA present in an individual’s urine or blood samples. The TCA blood test can demonstrate levels of TC in the bloodstream, which can help inform decisions around dosage. There are two types of urine test results, which may either show the levels of TCA or if there was TCA present.
Importantly, TCA drug tests can also be used to diagnose a TCA overdose or individuals at risk of overdose. The test will show whether an individual is taking an unprescribed TCA or consuming beyond the prescribed dosage and frequency. In these instances, this test is typically conducted within a wider drug toxicology screen (MedlinePlus, n.d).
Completing any type of drug test form can be incredibly informative and has the potential to save lives from overdose. This makes it essential to know how and when to conduct one.










